Overview
Clove oils, dried flower buds, leaves, and stems are used to make medicine. Clove oil contains a chemical called eugenol that might help decrease pain and fight infections. Clove is also a popular ingredient in cigarettes.
People commonly use clove for toothache pain during dental work, dental plaque, hangover, indigestion, and many other conditions, but there is no good scientific evidence to support these uses
Uses & Effectiveness
Possibly Effective for
- Pneumonia in people on breathing machines in the hospital. Use of a clove mouthwash might prevent pneumonia in people on breathing machines in the hospital.
Side Effects
When applied to the skin: Clove oil or cream containing clove flower is possibly safe. But applying clove oil in the mouth or on the gums can sometimes cause irritation and gum damage. Applying clove oil or cream to the skin can sometimes cause burning and skin irritation.
When inhaled: Smoke from clove cigarettes is likely unsafe and can cause side effects such as breathing problems and lung disease
Special Precautions and Warnings
When applied to the skin: Clove oil or cream containing clove flower is possibly safe. But applying clove oil in the mouth or on the gums can sometimes cause irritation and gum damage. Applying clove oil or cream to the skin can sometimes cause burning and skin irritation.
When inhaled: Smoke from clove cigarettes is likely unsafe and can cause side effects such as breathing problems and lung disease.
Pregnancy and breast-feeding: Clove is commonly consumed in foods. There isn't enough reliable information to know if clove is safe to use in larger amounts when pregnant or breast-feeding. Stay on the safe side and stick to food amounts.
Children: Clove oil is likely unsafe to take by mouth. Even small amounts of clove oil can cause severe side effects such as seizures, liver damage, and fluid imbalances.
Bleeding disorders: Clove oil contains a chemical called eugenol that seems to slow blood clotting. Taking clove oil might cause bleeding in people with bleeding disorders.
Surgery: Cloves contain chemicals that might affect blood sugar levels and slow blood clotting. It might interfere with blood sugar control or cause bleeding during or after surgery. Stop using clove at least 2 weeks before a scheduled surgery.
Interactions
Moderate Interaction
Be cautious with this combination
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Medications for diabetes (Antidiabetes drugs) interacts with CLOVE
Clove might lower blood sugar levels. Taking clove along with diabetes medications might cause blood sugar to drop too low. Monitor your blood sugar closely.
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Medications changed by the liver (Cytochrome P450 1A2 (CYP1A2) substrates) interacts with CLOVE
Some medications are changed and broken down by the liver. Clove might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
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Medications changed by the liver (Cytochrome P450 2C9 (CYP2C9) substrates) interacts with CLOVE
Some medications are changed and broken down by the liver. Clove might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
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Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with CLOVE
Some medications are changed and broken down by the liver. Clove might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
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Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates) interacts with CLOVE
Some medications are changed and broken down by the liver. Clove might change how quickly the liver breaks down these medications. This could change the effects and side effects of these medications.
Minor Interaction
Be watchful with this combination
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Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with CLOVE
Clove might slow blood clotting. Taking clove along with medications that also slow blood clotting might increase the risk of bruising and bleeding.
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Ibuprofen (Advil, others) interacts with CLOVE
Adding ibuprofen to clove oil before applying it to the skin might increase how much ibuprofen gets absorbed through the skin, possibly increasing side effects
Dosing
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